As part of its commitment to advancing immunological research and education, the International Union of Immunological Societies (IUIS) has compiled this comprehensive list of immunology databases. This initiative ensures that researchers, clinicians, and educators worldwide have easy access to essential immunological data, supporting scientific discoveries and clinical applications. Provided in collaboration with various immunological societies and organizations, this collection includes resources on immune cell profiling, antibody sequences, and disease-specific data.
We invite you to explore these databases and make the most of these valuable tools for your work!
Allergen Nomenclature Database that is approved by the World Health Organization and International Union of Immunological Societies Allergen Nomenclature Sub-Committee.
Human Cell Differentiation Molecules Database (HCDM) standardizes and characterizes leukocyte surface molecules critical to the immune system. Through HLDA Workshops, it assigns CD (cluster of differentiation) designations and maintains a database of related monoclonal antibodies. HCDM also provides resources like CD Maps, offering standardized flow cytometry data on antigen expression in immune cells.
Human Cell Differentiation Molecules CD Maps is a public resource from HCDM presenting standardized data on the expression of 110 CD markers across 47 human immune cell subsets. Generated across four labs using 8-color flow cytometry and QuantiBRITE beads, the dataset includes antibody binding capacity (ABC) values from 12 replicate samples. The project supports HCDM’s mission through dynamic profiling of CD1–CD100 molecules and complements the HLDA Workshops.
ICAP: International Consensus on ANA Patterns Database is the official site of the International Consensus on Antinuclear Antibody Patterns (ICAP), an initiative to standardize and classify HEp-2 IFA staining patterns. Formed under the IUIS Autoantibody Standardization Committee, ICAP provides high-quality reference images and promotes consistent terminology, including the preferred use of “HEp-2 IFA” over the outdated term “ANA.” ICAP uses “Anti-Cell (AC)” codes to label patterns, recognizing ongoing discussion around precise naming in autoantibody testing.
The IEI Committee provides an updated classification of over 180 inborn errors of immunity (IEIs), supporting clinical care, research, and healthcare policy worldwide. Used by clinicians, scientists, and health organizations, the classification guides diagnosis, treatment decisions, and funding. The latest version is available for download on the IUIS website, sortable by gene and inheritance, and suitable for designing sequencing panels and diagnostic tools.
Immuno-Polymorphism Database-KIR section Database is a centralized resource for curated human KIR (Killer-cell Immunoglobulin-like Receptor) gene sequences, which are highly polymorphic and part of the immunoglobulin superfamily. KIRs, encoded within the complex and diverse Leukocyte Receptor Complex (LRC), play key roles in immune regulation through inhibitory or activatory signaling. The database provides access to detailed sequence data and analysis tools to support research in immunogenetics.
Antinuclear Antibodies (ANA) Reference Standards helps laboratories improve standardization and quality control of testing of anti-nuclear and related autoantibodies. As part of this effort, IUIS Autoantibody Standardization Sub–Committee (ASC), in cooperation with the Centers for Disease Control (CDC), is making reference standards available for autoantibody specificities through Plasma Services Group, Inc. (PSG).