The IUIS Webinar Series was established at the beginning of 2020 as an online education programme with the aim to provide individuals from all around the world the opportunity to gain comprehensive knowledge on the latest COVID-19 research developments without the need of travelling in these uncertain times. This first series was a tremendous success:
internationally-acclaimed speakers shared their insights and latest research results on COVID-19-related topics in 20 webinars that welcomed more than 8,800 scientists from 86 countries.
For its second series, IUIS, in partnership with Immunopaedia, will broaden the scope to cover a variety of hot topics in
immunological research such as Autoimmunity, Infectious Diseases and Allergology.
The path to sterilizing immunity against tuberculosis
Date: March 8, 2021
Time: 3 PM CET
The participants will learn what immune factors contribute to control of M. tuberculosis at the individual granuloma level from studies in nonhuman primates. In addition, two scenarios that result in sterilizing immunity against tuberculosis will be presented.
Speaker: JoAnn Flynn
JoAnne Flynn has a Bachelor of Science degree in Biochemistry, from the University of California at Davis and a PhD from University of California at Berkeley in Microbiology and Immunology. Dr. Flynn’s first post-doc was with Dr. Magdalene So at the Scripps Clinic Research Institute and then joined the lab of Dr. Barry Bloom at Albert Einstein College of Medicine, as a Howard Hughes Research Associate, where she began her studies in tuberculosis. In 2018 she won the University of Pittsburgh School of Medicine Distinguished Mentor Award. In 2019 Dr. Flynn has been awarded the title of Distinguished Professor. Dr. Flynn directs a NIH T32 Training Program and has grants from NIH and the Bill and Melinda Gates Foundation. Her research in tuberculosis is focused on immunology, host-pathogen interactions, vaccines, and drugs, and she has developed and used non-human primate models for tuberculosis research over the past 20 years. She has multiple collaborations nationally and internationally. Dr. Flynn’s research uses cutting-edge tools and technologies to investigate the complexities of Mycobacterium tuberculosis infection, with a particular focus on lung and lymph node granulomas.
Moderator: Henry Mwandumba
Henry Mwandumba is Professor of Immunology and Infectious Diseases at the University of Malawi College of Medicine and Deputy Director of the Malawi Liverpool Wellcome Trust Clinical Research Programme (MLW) in Blantyre, Malawi. His research focuses on understanding the effects of HIV-1 infection on lung immunity and predisposition to respiratory infections, particularly tuberculosis. He is President of the Federation of African Immunological Societies (FAIS) and was awarded the 2019 Royal Society Africa Prize.
On demand Webinars
Please find below the on demand Webinars from the IUIS Webinar Series “Immunology without Borders”. This Series was started in February of 2021 and includes a wide arrays of topics.
Eric Vivier: Harnessing innate immunity in cancer therapy and beyond
New therapies that promote antitumor immunity have been recently developed. Most of these immunomodulatory approaches have focused on enhancing T-cell responses. Although these therapies have led to unprecedented successes, only a minority of cancer patients benefit from them, highlighting the need to identify new cells and molecules that could be exploited in the next generation of immunotherapy. Given the crucial role of innate immune responses in immunity, harnessing these responses opens up new possibilities for long-lasting, multilayered tumor control. We will present innovative anti-tumor therapies based on the manipulation of the innate immune system. In addition, given the urgent need for effective treatments for pneumonia in patients with COVID-19, the elucidation of the immune responses that occur during the course of COVID-19 could lead to the repurposing of approved immunomodulatory drugs and candidate drugs that have already been tested in clinical trials. Along this line, we will present our results indicating the association of COVID-19 inflammation with activation of the C5a–C5aR1 axis.
Pamela Ohashi: Immunoregulation and the tumor microenvironment
Although PD-1 blockade has transformed cancer treatment, a deeper understanding of tumor immunobiology and inhibitory mechanisms are needed to take immunotherapy to the next level. This webinar will cover topics including the cell types that express key B7 family members and their receptors including PD-L1, B7-H3, B7-H4 and PD-1 and discuss whether these findings align with the traditional views for what is going on in the tumor microenvironment. In addition, it will cover unexpected immunoregulatory mechanisms that we have found focussing on innate lymphoid cells.
This webinar is supported by: Thermo Fisher Scientific
The production of this webinar is supported by Thermo Fisher Scientific. Thermo Fisher Scientific has had no influence on the content, and full editorial control remains the sole responsibility of IUIS.
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